0
Article Tier 2 Environmental Sources Human Health Effects Sign in to save

Plastic and Human Health: A Micro Issue?

Environmental Science & Technology 2017 3060 citations

AI summary Read the abstract

This review evaluates the potential human health impacts of microplastic exposure through food and air, drawing on evidence from particle toxicology and related fields. Researchers note that if inhaled or ingested, microplastics could accumulate in tissues and cause localized inflammation, while chemical additives and adsorbed pollutants may leach out and cause additional toxic effects. The paper emphasizes that chronic, long-term exposure is likely the greater concern, though current data on actual human exposure levels remains limited.

Microplastics are a pollutant of environmental concern. Their presence in food destined for human consumption and in air samples has been reported. Thus, microplastic exposure via diet or inhalation could occur, the human health effects of which are unknown. The current review article draws upon cross-disciplinary scientific literature to discuss and evaluate the potential human health impacts of microplastics and outlines urgent areas for future research. Key literature up to September 2016 relating to accumulation, particle toxicity, and chemical and microbial contaminants was critically examined. Although microplastics and human health is an emerging field, complementary existing fields indicate potential particle, chemical and microbial hazards. If inhaled or ingested, microplastics may accumulate and exert localized particle toxicity by inducing or enhancing an immune response. Chemical toxicity could occur due to the localized leaching of component monomers, endogenous additives, and adsorbed environmental pollutants. Chronic exposure is anticipated to be of greater concern due to the accumulative effect that could occur. This is expected to be dose-dependent, and a robust evidence-base of exposure levels is currently lacking. Although there is potential for microplastics to impact human health, assessing current exposure levels and burdens is key. This information will guide future research into the potential mechanisms of toxicity and hence therein possible health effects.

More Papers Like This

Article Tier 2

Environmental exposure to microplastics: An overview on possible human health effects

AI summary Read the abstract

This review examines the potential health effects of human exposure to microplastics through ingestion, inhalation, and skin contact. Researchers found that microplastic exposure may cause oxidative stress, inflammation, and immune system disruption, with the body's inability to break down synthetic particles potentially leading to chronic inflammation. The study emphasizes that while evidence of harm is growing, microplastic toxicity varies greatly depending on particle properties, concentration, and individual susceptibility.

Review Tier 2

Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects

AI summary Read the abstract

This review summarizes existing research on how microplastics are found throughout the environment and in human samples, entering the body through food, air, and skin contact. Lab studies in cells and animals show microplastics can cause oxidative stress, DNA damage, immune reactions, brain toxicity, and reproductive harm, and early human health data links microplastic exposure to several chronic diseases.

Review Tier 2

A review of data for quantifying human exposures to micro and nanoplastics and potential health risks

AI summary Read the abstract

This review synthesizes data on human exposure to micro- and nanoplastics through air, water, and food, and examines the potential health effects. Researchers found evidence of respiratory, liver, immune, and gastrointestinal impacts in humans and mammals exposed to elevated plastic particle levels, with toxicity varying by plastic type and size. The study highlights that while growing evidence links plastic particle exposure to health concerns, significant data gaps remain in quantifying actual human intake and long-term risks.

Article Tier 2

The potential effects of microplastics on human health: What is known and what is unknown

AI summary Read the abstract

This review summarizes what is currently known about how microplastics might affect human health, noting that while contamination is widespread in food, water, and air, direct evidence of harm in humans is still limited. Studies in animals and cell cultures suggest microplastics could trigger immune responses, cause inflammation, and affect reproduction and development. The authors call for more rigorous clinical studies to determine whether the levels of microplastics that people actually encounter pose real health risks.

Systematic Review Tier 1

Human Exposure to Microplastics: Toxicological Mechanisms and Potential Health Implications - a Narrative Review

AI summary Read the abstract

Tiny plastic particles from our food, water, and air are showing up inside the human body, and lab studies suggest they could trigger cell damage, inflammation, and hormone disruption. This review pulls together existing research to show that while the potential risks are concerning, most evidence so far comes from test tubes and animal studies—so scientists still can't say for certain whether microplastics are directly causing specific diseases in people. More real-world human studies are needed before we know exactly how worried to be.

Research digests by email

When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.

Email me about

Share this paper