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Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio)
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Researchers exposed zebrafish to polystyrene microplastics combined with cadmium for three weeks and found that the presence of microplastics significantly increased cadmium accumulation in the liver, gut, and gills. The combined exposure caused greater oxidative damage, tissue inflammation, and disruption of protective gene activity than either pollutant alone. The study demonstrates that microplastics can enhance the toxicity of heavy metals in fish by acting as carriers that increase the body's uptake of harmful substances.
As the accumulation of microplastics (MPs) in the environment continues to rise, more concerns focus on the health risk of combined exposure to MPs and other contaminants. The aim of this study is to investigate the influences of MPs on the tissue-accumulation of cadmium (Cd) in zebrafish and explore the related chronic toxic effects induced by combined exposure of Cd and MPs. After co-exposure to MPs and Cd for 3 weeks, 20 and 200 μg/L MPs increased the accumulation of Cd in zebrafish livers (46% and 184%), guts (10% and 25%) and gills (9% and 46%). The Cd accumulation was gill > gut > liver. Comprehensive analyzes of biochemical biomarkers, histopathological observation and functional gene expression firstly demonstrated that the presence of MPs enhanced the toxicity of Cd on zebrafish and the combined exposure caused oxidative damage and inflammation in zebrafish tissues. Collectively, our results highlight the chronic effects of combined exposure to MPs and heavy metals.
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Additive effects of microplastics on accumulation and toxicity of cadmium in male zebrafish
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Researchers exposed adult zebrafish to polyethylene microplastics and cadmium, both individually and in combination, for 21 days. They found that microplastics and cadmium together produced additive toxic effects, increasing cadmium accumulation in fish tissues, altering behavior, and causing more severe organ damage. The study suggests that microplastics in contaminated waterways may worsen the harmful effects of heavy metals on aquatic life.
Comparison of the combined toxicity of polystyrene microplastics and different concentrations of cadmium in zebrafish
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Researchers studied the combined toxic effects of polystyrene microplastics and cadmium at different concentrations in zebrafish over a 10-day exposure period. The study found that microplastics could either amplify or reduce cadmium toxicity depending on the metal concentration, affecting survival, growth, and antioxidant responses in complex ways.
Microplastics aggravate the adverse effects of methylmercury than inorganic mercury on zebrafish (Danio rerio)
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Researchers exposed zebrafish embryos to polystyrene microplastics combined with two forms of mercury and found that the microplastics significantly increased the accumulation of methylmercury in the fish. The combination of microplastics and methylmercury caused worse developmental abnormalities, delayed hatching, and greater oxidative stress than either pollutant alone. The study suggests that microplastics can act as carriers for toxic metals, amplifying their harmful effects on aquatic organisms.
Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio)
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Researchers exposed zebrafish embryos to polystyrene microplastics combined with cadmium to assess their combined toxic effects on aquatic organisms. The study found that co-exposure produced greater negative impacts on survival and heart rate than either pollutant alone, with toxicity increasing in a concentration-dependent manner.
Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish ( Danio rerio )
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Researchers studied the combined effects of microplastics and chemical contaminants like PCBs and methylmercury on zebrafish organs over three weeks of exposure. They found that microplastics carrying adsorbed contaminants produced the most significant effects, particularly on the liver, compared to either microplastics or contaminants alone. The results indicate that microplastics may act as carriers that increase the delivery of harmful chemicals to organisms' tissues.
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