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Microplastics in human body: accumulation, natural clearance, and biomedical detoxification strategies
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This review covers how microplastics enter the human body through air, water and food, and where they accumulate. It assesses what is known about how the body handles the particles on its own, including immune responses, and finds the evidence limited. It also surveys proposed biomedical approaches, none of them established.
Microplastics have become ubiquitous in modern environments, entering the human body through multiple pathways, including air, water, and food. Recent evidence shows that microplastics penetrate deep into the human body and accumulate in tissues. Despite escalating exposure to microplastics and growing concerns about potential toxicity, strategies for microplastic clearance from the body have yet to be explored. This review summarizes current knowledge on exposure pathways, distribution, accumulation mechanisms, and health risks of microplastics and critically evaluates natural clearance mechanisms in human and their limitations. Further, we investigate potential biomedical strategies for microplastic clearance and detoxification and synthesize considerations for clinical translation.
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This review summarizes existing research on how tiny plastic particles called microplastics and nanoplastics enter the human body through food, water, air, and skin contact. Studies cited suggest these particles may build up in tissues and are linked to inflammation, immune problems, and other health issues, though long-term human health risks remain unclear.
[Human Accumulation and Toxic Effects of Microplastics：A Critical Review].
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This review summarizes how microplastics enter the human body through food, drinking water, and air, and where they tend to accumulate in organs and tissues. Researchers found evidence that microplastics can trigger inflammatory responses and oxidative stress in the body. The study calls for more research into the long-term health effects of continuous microplastic exposure in humans.
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This review summarizes how microplastics enter the human body through food, water, and air, and what happens when they encounter the body's protective barriers like the gut lining, skin, and blood-brain barrier. Smaller microplastics can cross these barriers and accumulate in organs, potentially causing inflammation and other harmful effects. The review also covers emerging methods for removing microplastics from the environment to reduce human exposure.
Microplastics in the human body: A comprehensive review of exposure, distribution, migration mechanisms, and toxicity
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This comprehensive review pulls together research on how microplastics enter the human body through food, air, and skin contact, and where they accumulate in organs and tissues. The review discusses how particle size determines whether microplastics can cross biological barriers like the gut lining and blood-brain barrier. The authors conclude that microplastics pose significant health risks and call for more research into their long-term effects.
Microplastics and Human Health: A Comprehensive Review on Exposure Pathways, Toxicity, and Emerging Risks
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This comprehensive review examines microplastic exposure pathways in humans, methods of detection, and the potential toxic effects on various biological systems. The study highlights growing evidence that microplastics can enter the body through ingestion, inhalation, and dermal contact, and may affect multiple organ systems, though significant uncertainties remain about long-term health outcomes.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.