Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Marine & Wildlife Nanoplastics Sign in to save

Toxicity comparison of nano-sized and micron-sized microplastics to Goldfish Carassius auratus Larvae

Journal of Hazardous Materials 2020 304 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 60 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Yingying Zhang, Yingying Zhang, Hui Yang Yingying Zhang, Yingying Zhang, Hui Yang Hui Yang Yingying Zhang, Hui Yang Haoran Xiong, Kaihang Mi, Kaihang Mi, Hui Yang Xue Wen, Hui Yang Hui Yang Wenzhi Wei, Hui Yang Hui Yang Hui Yang Hui Yang Yingying Zhang, Yingying Zhang, Yingying Zhang, Yingying Zhang, Wenzhi Wei, Yingying Zhang, Yingying Zhang, Hui Yang Yingying Zhang, Hui Yang

Summary

Researchers compared the toxic effects of nano-sized and micron-sized polystyrene microplastics on goldfish larvae over seven days. Both sizes accumulated in the digestive tract and caused oxidative stress, tissue damage, and increased heart rate at high concentrations. Notably, the nano-sized particles were able to penetrate through the skin into muscle tissue and cause nerve fiber damage, suggesting they may be more hazardous than larger microplastics.

Body Systems

Cardiovascular Digestive Hepatic Integumentary Musculoskeletal

Models

Fish other

Plastic pollution is one of the most serious environmental issues worldwide. The negative influence of plastics on aquatic organisms has increasingly concerned, especially the influence of microplastic (MPs). In the present study, the toxicology of nano-sized MPs (nMPs) and micron-sized MPs (mMPs) were comparatively studied. Goldfish larvae were exposed to 10, 100 and 1000 μg/L nMPs and mMPs for 1, 3 and 7 days. The enrichment of MPs, body length, heart rate, motor ability, microscopic and ultrastructure of intestine, liver, gill and muscle tissue, as well as the oxidative stress were analyzed. Results showed that both 70 nm and 50 μm MPs were accumulated in the digestive tract of larvae. MPs at high concentrations could induce oxidative stress, destroy intestine, liver and gill tissues, increase heart rate, and inhibit growth and swimming speed of the larvae. The most important finding was that nMPs could enter into the muscle tissue through the epidermis of the larvae. It could cause damage to muscle tissue, destroy nerve fibers, inhibit acetylcholinase (AchE) activity, and show great adverse effects on larval movement than mMPs. In conclusion, both nMPs and mMPs at higher concentrations can cause damage to fish larvae and nMPs are potentially more hazardous.

Read via DOI PubMed

Share this paper

Post Share Share Pin Email