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Article Tier 2 Human Health Effects Nanoplastics Sign in to save

Micro- and nanoplastic exposure and metabolic disruption: A review on their emerging role in the pathogenesis of diabetes

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Researchers reviewed human exposure pathways to microplastics and nanoplastics through seafood, salt, drinking water, inhalation, and skin contact, examining how these particles cross biological barriers to reach organs and trigger oxidative stress, inflammation, and endocrine disruption with poorly understood long-term consequences.

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This review synthesizes evidence that microplastics and nanoplastics have been detected in human blood, placenta, breast milk, and stool, with emerging associations between internal MNP burdens and inflammatory, cardiometabolic, and potential reproductive effects. Humans are exposed through ingestion, inhalation, skin contact, and medical interventions, making microplastic accumulation in the body a pressing public health concern requiring urgent research into clinical health outcomes.

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