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Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

Particle and Fibre Toxicology 2020 428 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 60 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Sara Fournier, Jeanine N. D’Errico, Sara Fournier, Sara Fournier, Phoebe A. Stapleton Phoebe A. Stapleton Sara Fournier, Sara Fournier, Sara Fournier, Sara Fournier, Sara Fournier, Sara Fournier, Jeanine N. D’Errico, Sara Fournier, Sara Fournier, Jeanine N. D’Errico, Sara Fournier, Jeanine N. D’Errico, Jeanine N. D’Errico, Derek Adler, Derek Adler, Phoebe A. Stapleton Derek Adler, Derek Adler, Derek Adler, Phoebe A. Stapleton Derek Adler, Derek Adler, Derek Adler, Stamatina Kollontzi, Phoebe A. Stapleton Phoebe A. Stapleton Stamatina Kollontzi, Stamatina Kollontzi, Stamatina Kollontzi, Stamatina Kollontzi, Stamatina Kollontzi, Stamatina Kollontzi, Stamatina Kollontzi, Michael Goedken, Michael Goedken, Michael Goedken, Michael Goedken, Michael Goedken, Michael Goedken, Edward J. Yurkow, Michael Goedken, Michael Goedken, Michael Goedken, Michael Goedken, Phoebe A. Stapleton Laura Fabris, Michael Goedken, Michael Goedken, Laura Fabris, Laura Fabris, Michael Goedken, Michael Goedken, Laura Fabris, Edward J. Yurkow, Edward J. Yurkow, Edward J. Yurkow, Phoebe A. Stapleton Edward J. Yurkow, Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Edward J. Yurkow, Michael Goedken, Michael Goedken, Michael Goedken, Michael Goedken, Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton Phoebe A. Stapleton

Summary

Researchers exposed pregnant mice to nanoscale polystyrene particles through inhalation and tracked where the particles traveled. They found that the nanoplastics crossed from the lungs into the bloodstream and accumulated in both placental and fetal tissues, confirming that inhaled plastic nanoparticles can reach developing offspring during pregnancy.

These studies confirm that maternal pulmonary exposure to nanopolystyrene results in the translocation of plastic particles to placental and fetal tissues and renders the fetoplacental unit vulnerable to adverse effects. These data are vital to the understanding of plastic particulate toxicology and the developmental origins of health and disease.

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