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Article Tier 2 Human Health Effects Reproductive & Development Sign in to save

Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

Particle and Fibre Toxicology 2020 428 citations

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Researchers exposed pregnant mice to nanoscale polystyrene particles through inhalation and tracked where the particles traveled. They found that the nanoplastics crossed from the lungs into the bloodstream and accumulated in both placental and fetal tissues, confirming that inhaled plastic nanoparticles can reach developing offspring during pregnancy.

These studies confirm that maternal pulmonary exposure to nanopolystyrene results in the translocation of plastic particles to placental and fetal tissues and renders the fetoplacental unit vulnerable to adverse effects. These data are vital to the understanding of plastic particulate toxicology and the developmental origins of health and disease.

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Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

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Researchers found that nanoscale polystyrene particles inhaled by pregnant mice were able to cross into the placenta and deposit in fetal tissues. The findings raise concerns about potential developmental risks from airborne nanoplastic exposure during pregnancy.

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Nanopolystyrene Translocation and Fetal Deposition After Acute Lung Exposure During Late-Stage Pregnancy

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Nanopolystyrene particles inhaled by pregnant mice during late pregnancy crossed into the bloodstream and deposited in fetal tissues. This finding raises concern that airborne nanoplastics could pose a risk to fetal development, especially given growing human exposure to plastic particles in indoor and outdoor air.

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