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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Reproductive & Development Sign in to save

Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

Particle and Fibre Toxicology 2020 428 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Sara Fournier, Jeanine N. D’Errico, Derek Adler, Stamatina Kollontzi, Michael Goedken, Laura Fabris, Edward J. Yurkow, Phoebe A. Stapleton

Summary

Researchers exposed pregnant mice to nanoscale polystyrene particles through inhalation and tracked where the particles traveled. They found that the nanoplastics crossed from the lungs into the bloodstream and accumulated in both placental and fetal tissues, confirming that inhaled plastic nanoparticles can reach developing offspring during pregnancy.

These studies confirm that maternal pulmonary exposure to nanopolystyrene results in the translocation of plastic particles to placental and fetal tissues and renders the fetoplacental unit vulnerable to adverse effects. These data are vital to the understanding of plastic particulate toxicology and the developmental origins of health and disease.

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