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Micro/nanoplastics induce thyroid follicular cell pyroptosis to trigger thyrotoxicity by activating NF-κB signaling
Summary
Researchers investigated how micro- and nanoplastics affect thyroid health and found that these particles can trigger a specific form of cell death called pyroptosis in thyroid follicular cells. The study suggests that this process is activated through NF-kB signaling pathways, providing new mechanistic insights into how environmental plastic pollution may contribute to thyroid toxicity.
Collectively, these findings provide novel mechanistic insights into MNP-induced thyroid toxicity and highlight the critical role of follicular cell pyroptosis, contributing to our understanding of the adverse health consequences associated with environmental plastic pollution.