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Enzymes in the Removal of Harmful Substances: The Potential of Biotechnology in Environmental Protection

Earth Environmental Sustainability 2025
Agnieszka Rybarczyk, Jakub Zdarta

Summary

This review examines the potential of enzymes as sustainable, highly specific tools for removing harmful environmental pollutants including pesticides, pharmaceuticals, heavy metals, dyes, and microplastics under mild conditions without generating toxic by-products. The authors highlight innovations in enzyme immobilisation, microbial consortia, and hybrid technologies as strategies to enhance efficiency and broaden the practical applicability of biotechnology-based environmental remediation.

In the face of growing environmental pressures, enzymes are emerging as powerful and versatile tools for combating pollution. With their exceptional specificity, ability to function under mild conditions, and minimal environmental impact, enzymes offer a sustainable alternative to traditional remediation methods. They can effectively break down and neutralize a wide range of pollutants—including pesticides, pharmaceuticals, heavy metals, dyes, and microplastics—without generating toxic by-products. Innovations such as enzyme immobilization, microbial consortia, and hybrid technologies have significantly enhanced their stability and performance in real-world conditions. Advances in protein engineering and the use of artificial intelligence now enable the design of tailor-made enzymes with improved resilience and substrate range. Enzymes also play a vital role in the circular economy by transforming waste into valuable secondary raw materials, biofuels, and biodegradable products. While challenges remain in scaling up these technologies and reducing costs, the potential of enzyme-based biotechnologies is immense, positioning them as a promising path toward environmentally friendly and efficient solutions for pollution control, resource recovery, climate-resilient development, and as a cornerstone of future environmental strategies.

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