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Microbial Enzymes Used in Bioremediation

Journal of Chemistry 2021 265 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 65 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Sobika Bhandari, Darbin Kumar Poudel, Rishab Marahatha, Sonika Dawadi, Karan Khadayat, Sitaram Phuyal, Shreesti Shrestha, Santosh Gaire, Kusum Basnet, Uddhav Khadka, Niranjan Parajuli

Summary

This review covers microbial enzymes that can break down environmental pollutants, including some types of plastic polymers. Enzymes like laccases, hydrolases, and lipases show promise for degrading plastics and other harmful substances in the environment. While not focused solely on microplastics, the research suggests that enzyme-based bioremediation could eventually help reduce microplastic pollution in soil and water.

Emerging pollutants in nature are linked to various acute and chronic detriments in biotic components and subsequently deteriorate the ecosystem with serious hazards. Conventional methods for removing pollutants are not efficient; instead, they end up with the formation of secondary pollutants. Significant destructive impacts of pollutants are perinatal disorders, mortality, respiratory disorders, allergy, cancer, cardiovascular and mental disorders, and other harmful effects. The pollutant substrate can recognize different microbial enzymes at optimum conditions (temperature/pH/contact time/concentration) to efficiently transform them into other rather unharmful products. The most representative enzymes involved in bioremediation include cytochrome P450s, laccases, hydrolases, dehalogenases, dehydrogenases, proteases, and lipases, which have shown promising potential degradation of polymers, aromatic hydrocarbons, halogenated compounds, dyes, detergents, agrochemical compounds, etc. Such bioremediation is favored by various mechanisms such as oxidation, reduction, elimination, and ring-opening. The significant degradation of pollutants can be upgraded utilizing genetically engineered microorganisms that produce many recombinant enzymes through eco-friendly new technology. So far, few microbial enzymes have been exploited, and vast microbial diversity is still unexplored. This review would also be useful for further research to enhance the efficiency of degradation of xenobiotic pollutants, including agrochemical, microplastic, polyhalogenated compounds, and other hydrocarbons.

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