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Screening of differentially expressed genes and functional enrichment analysis of crossover genes in allergic rhinitis.

Figshare 2025
Yaojun Wang (309584), Dandan Xu (149923)

Summary

This figure supplement presents bioinformatics results from a study identifying crossover genes between microplastic toxicity targets and allergic rhinitis differentially expressed genes, including volcano plots, Venn diagrams, and pathway enrichment analyses.

A.The red and green colors indicate significantly upregulated and downregulated genes. B.Scatter plot of differentially expressed genes in AR. C.The Venn diagram illustrates the intersection of genes between microplastic toxicity targets and differentially expressed genes for AR. D.The clustered heatmap shows the expression profile data of the 15 intersecting genes in AR. Red color represents gene expression upregulation and blue color represents gene expression downregulation. E-G. Biological process (BP), cellular composition (CC), and molecular function (MF) were presented using bubble plots. The size of the bubbles represents the number of enriched genes, and the color represents the significance. H. KEGG analysis results were presented using string diagrams, with different colors indicating different significant pathways and their associated genes.

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