We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Unravelling ultrafine particulate matter and micro nano plastic's mechanisms of impact on fetal health (UPRISE)
AI summary Read the abstract
The UPRISE research project is investigating how airborne ultrafine particles and micro-nanoplastics affect fetal health, using exposure modeling, biological pathway analysis, and a clinical study of pregnant women to identify mechanisms linking prenatal pollution to noncommunicable disease risk.
The UPRISE project investigates how air pollution—specifically ultrafine particles (UFPs) and micro-nanoplastics(MNPs)—affects fetal development and increases the risk of adverse birth outcomes (ABOs) linked to later noncommunicablediseases (NCDs). By developing exposure databases, advanced models, and a clinical study onpregnant participants, UPRISE will uncover key biological pathways underlying these effects. The project will buildcausal models to establish evidence-based links between pollutant exposure and ABOs and will translate findingsinto policy tools to inform European air quality standards. Ultimately, UPRISE aims to reduce the long-term healthburden of pollution-related prenatal impacts.
More Papers Like This
Unravelling ultrafine particulate matter and micro nano plastic's mechanisms of impact on fetal health (UPRISE)
AI summary Read the abstract
The UPRISE project described here investigates how ultrafine particles and micro-nanoplastics from air pollution affect fetal development and birth outcomes, developing exposure databases, advanced models, and a clinical study on pregnant participants to build causal evidence.
Investigating Exposure and Hazards of Micro- and Nanoplastics During Pregnancy and Early Life (AURORA Project): Protocol for an Interdisciplinary Study (Preprint)
AI summary Read the abstract
The AURORA project protocol describes an interdisciplinary European study investigating micro- and nanoplastic exposures and their biological effects during pregnancy and early life, enrolling mother-child cohorts and combining biomonitoring with mechanistic research. The project aims to identify critical windows of developmental vulnerability to plastic pollution.
The Intrauterine Exposome: A Scoping Review of the Evidence Chain from Maternal Exposure to Foetal Effect and Later-Life Health
AI summary Read the abstract
This review summarizes existing research on how factors during pregnancy, including tobacco smoke, chemicals, air pollution, stress, nutrition and microplastics, may pass from mother to foetus and affect development. It proposes a framework tracing exposure from the mother through the placenta to the foetus, noting that exposure does not always mean the foetus was affected, and identifies gaps for future study.
Placental Micro- and Nanoplastic Contamination: A Systematic Review of Eco-Exposome Pathways to Preterm Birth and Neonatal Outcomes
AI summary Read the abstract
This systematic review examined evidence that micro- and nanoplastics have been found in human placentas and may be linked to preterm birth. The particles appear to cause inflammation, oxidative stress, and disruption of placental function through multiple molecular pathways, raising concerns about the impact of plastic pollution on pregnancy outcomes and newborn health.
Placental micro- and nanoplastic contamination: A systematic review of eco-exposome pathways to preterm birth and neonatal outcomes
AI summary Read the abstract
Researchers systematically reviewed 20 studies detecting micro- and nanoplastics in human placental tissue, cord blood, and amniotic fluid, finding higher MNP burdens in preterm versus term placentae and identifying oxidative stress, ferroptosis, impaired trophoblast invasion, and inflammatory signaling as converging molecular pathways linking placental MNP contamination to preterm birth and neonatal morbidity.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.