We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Microplastics aggravate the bioaccumulation and toxicity of coexisting contaminants in aquatic organisms: A synergistic health hazard
Summary
Researchers conducted a quantitative meta-analysis of 870 endpoints from 40 studies to evaluate whether microplastics increase the bioaccumulation and toxicity of co-occurring contaminants in aquatic organisms. They found that microplastics significantly increased co-contaminant bioaccumulation by 31% and exacerbated toxicity by 18%, with effects manifesting as increased oxidative stress, endocrine disruption, and immunotoxicity. The study confirms that microplastics act as vectors that amplify the hazards of other environmental pollutants.
There are ongoing controversies regarding the effects of microplastics (MPs) on the bioaccumulation and toxicity of coexisting contaminants in aquatic organisms. This study aims to quantitatively evaluate this issue based on 870 endpoints from 40 publications. It was shown that the presence of MPs significantly increased the bioaccumulation of co-contaminants by 31%, with high statistical power and without obvious publication bias. The aggravated bioaccumulation was also revealed by the strongly positive correlation between bioconcentration factors in the presence and the absence of MPs. Furthermore, the subgroup/regression analyses indicated that the vector effect of MPs on other chemicals was affected by multiple factors and their interactions, such as particle size and exposure time. In addition, a relatively comprehensive biomarker profile was recompiled from included studies to assess the changes in toxicity caused by combined exposure. Results confirmed that the presence of MPs obviously exacerbated the toxicity of co-contaminants by 18%, manifested by the potentiated cytotoxicity, endocrine disruption, immunotoxicity and oxidative stress, implying a synergistic health hazard. Ultimately, the mismatches between laboratory and field conditions were discussed, and the recommendations for future research were offered.
Sign in to start a discussion.
More Papers Like This
Effects of microplastics on the toxicity of co-existing pollutants to fish: A meta-analysis
Meta-analysis of 1,380 biological endpoints from 55 studies found that microplastics in co-existing pollutant solutions significantly increased toxicity to fish beyond what the pollutants caused alone, particularly elevating immune system damage, metabolic disruption, and oxidative stress. The effect depended on fish life stage and microplastic size, but not on pollutant or polymer type.
Unlocking the combined impact of microplastics and emerging contaminants on fish: A review and meta-analysis
This meta-analysis found that combined exposure to microplastics and emerging contaminants adversely affects fish reproduction, development, and neurotoxicity beyond what either pollutant causes alone. Microplastics with higher adsorption capacities led to more severe outcomes by concentrating and delivering co-contaminants, though exposure duration did not correlate with oxidative stress levels.
Fate of microplastics and emerging contaminants: Mechanisms of interactions, bioaccumulation and combined toxicity to aquatic organisms
This review summarizes how microplastics interact with other emerging contaminants in water, finding that microplastics can absorb pollutants at concentrations up to a million times higher than surrounding water and carry them into living organisms. The combined toxicity of microplastics plus these hitchhiking chemicals is often greater than either alone, and these pollutants can reach humans through the food chain.
Ecotoxicology of microplastics in water ecosystems and aquatic organisms: A review of synergistic and antagonistic effects of microplastics on other xenobiotics
This review examines the ecotoxicological effects of microplastics in aquatic ecosystems, focusing on how they interact with other pollutants like heavy metals, organic contaminants, and pathogens. The study highlights that microplastics can adsorb and transport these pollutants through synergistic or antagonistic interactions, leading to oxidative stress, endocrine disruption, and reproductive impairment in exposed organisms, with potential for biomagnification up the food chain.
Meta-analysis unravels the complex combined toxicity of microplastics and antibiotics in aquatic ecosystems
A meta-analysis of 730 datasets found that microplastics amplify antibiotic accumulation in aquatic organisms and worsen effects on growth, development, and immune function, but paradoxically appear to mitigate reproductive toxicity from antibiotics. The impact depends on biological response pathway, microplastic concentration, antibiotic properties, and exposure time, with an inverse relationship between antibiotic toxicity and both microplastic concentration and exposure duration.