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Increase in germline methyltransferases governing the methylation of histone H3K9 is associated with transgenerational nanoplastic toxicity in Caenorhabditis elegans

Environmental Science Nano 2021 27 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Le Zhang, Shuting Wang, Yue Zhao, Kun Bi, Dayong Wang

Summary

Researchers found that increased germline methyltransferases responsible for histone H3K9 methylation are associated with transgenerational nanoplastic toxicity in the nematode C. elegans, suggesting epigenetic mechanisms underlie cross-generational plastic harm.

Our data demonstrated the association of the increase in germline methyltransferases required for methylation of H3K9 with transgenerational nanoplastic toxicity in nematodes.

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