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Competitive and/or cooperative interactions of graphene-family materials and benzo[a]pyrene with pulmonary surfactant: a computational and experimental study
Particle and Fibre Toxicology2021
7 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 30
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Researchers studied how graphene-based nanomaterials and benzo[a]pyrene — a toxic pollutant — interact with the thin fluid layer lining the lungs, finding that graphene readily absorbs the pollutant and carries it to the lung surface where it can disrupt the protective surfactant layer. This suggests that nanomaterials, similar to nanoplastics, could act as carriers that concentrate and deliver harmful chemicals deeper into the respiratory system.
GFMs showed high adsorption capacity towards BaPs to form nanocomposites. Upon deposition of GFMs carrying BaPs at the alveolar air-water interface covered by a thin PS layer, the interactions of GFM-PS, GFM-BaP and BaP-PS determined the interfacial processes of BaP solubilization, GFM translocation and PS perturbation.