We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Nanoplastics Cause Transgenerational Toxicity Through Inhibiting Germline Microrna Mir-38 in C. Elegans
No summary available — this paper's abstract is not included in the open metadata provided by the publisher. Learn why →
More Papers Like This
Nanoplastics cause transgenerational toxicity through inhibiting germline microRNA mir-38 in C. elegans
AI summary Read the abstract
Researchers used the model organism C. elegans to investigate how nanoplastic exposure causes transgenerational toxicity through effects on germline microRNA. The study found that polystyrene nanoparticles decreased expression of germline miRNA mir-38, and that overexpressing this miRNA conferred resistance to transgenerational toxicity. The findings suggest that nanoplastics can cause heritable toxic effects across generations by disrupting germline gene regulation.
Nanoplastic Exposure at Predicted Environmental Concentrations Induces Activation of Germline Ephrin Signal Associated with Toxicity Formation in the Caenorhabditis elegans Offspring
AI summary Read the abstract
Researchers discovered that nanoplastic exposure at environmentally relevant concentrations activates the germline Ephrin signaling pathway in C. elegans, revealing a molecular mechanism underlying transgenerational toxicity formation in offspring.
The Toxicity of (Nano)Microplastics on C. elegans and Its Mechanisms
AI summary Read the abstract
Researchers reviewed the toxicological effects of micro- and nanoplastics on the model organism Caenorhabditis elegans, finding that these particles cause oxidative stress, reproductive impairment, developmental delays, and neurological dysfunction, with nanoplastics generally more toxic than microplastics due to their greater cellular penetration.
Unveiling micro-nanoplastics (MNPs) induced developmental toxicity, transgenerational transport and associated signaling pathways
AI summary Read the abstract
Tiny plastic particles from our environment can pass from a mother to her baby through the placenta and breast milk, and this review of existing animal research shows these particles can build up in offspring and potentially disrupt healthy development, causing issues like inflammation, cell damage, and hormone problems. While most of this evidence comes from animal studies so far, it's a wake-up call that plastic pollution may affect not just the people exposed to it, but their children too, making it worth pushing for both more research in humans and stronger policies to cut down plastic exposure.
Epigenetic response to nanopolystyrene in germline of nematode Caenorhabditis elegans
AI summary Read the abstract
Germline microRNA mir-38 was found to be upregulated in the nematode C. elegans following exposure to 100-nm polystyrene nanoplastics, triggering an epigenetic response that reduced expression of downstream regulatory genes. This miRNA-mediated pathway represents a novel epigenetic mechanism by which nanoplastic exposure propagates molecular changes in reproductive tissues.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.