Back to papers
0
Systematic Review ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 1 ? Systematic review or meta-analysis. Synthesizes findings across many studies. Strongest evidence. Human Health Effects Marine & Wildlife Policy & Risk Reproductive & Development Sign in to save

A Systematic Review of the Effects of Bisphenol Analogs on Embryonic Development and Cytoskeletal Organization of Zebrafish (Danio rerio) Embryos

Biointerface Research in Applied Chemistry 2022 5 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Razif Dasiman, Norazmir Md Nor, Zolkapli Eshak, S. M. M. Syairah, Mohd Hatta Abdul Mutalip, Rohmah Suwandi, Habsah Bidin, Razif Abas, T Chioccarelli, F Manfrevola, M Migliaccio, L Altucci, V Porreca, S Fasano, G Cobellis, M Cescon, R Meli, A Monnolo, C Annunziata, C Pirozzi, M Ferrante, C Rhodes, S Almeida, A Raposo, M Almeida-Gonzlez, C Carrascosa, L Canesi, E Fabbri, G Larsen, R Dasiman, S Zulazlan, Z Eshak, S Syairah, M Mutalip, A Rambli, M Malek, N Khan, Joao Pinto Da Costa, T, -S, A, S Rosa, V Nascimento, C Rogrigues, S Xu, H Zhang, P He, L Shao, J Corrales, L Kristofco, W Baylor Steele, B Yates, C Breed, E Spencer Williams, B Brooks, R Kristanti, T Hadibarata, H Al Qahtani, A Careghini, A Mastorgio, S Saponaro, E Sezenna, A Bisphenol, J Sajiki, J Yonekubo, L Barboza, S Cunha, C Monteiro, J Fernandes, L Guilhermino, N Wu, F Seebacher, C Han, Y Wei, Y Geng, Y Cui, S Li, Y Bao, W Shi, J Rochester, Z Shaoqing, J.-Q Jiang, F Liguori, C Moreno-Marrodan, P Barbaro, M Moon, D Goldinger, A Demierre, O Zoller, H Rupp, H Reinhard, R Magnin, T Becker, M Bourqui-Pittet, S Song, T Ruan, T Wang, R Liu, G Jiang, H Okazaki

Summary

This systematic review examines how bisphenol A analogs, chemicals used as replacements for BPA in plastics, affect zebrafish embryo development. These findings are concerning because BPA substitutes are found in many plastic products and may cause similar hormone-disrupting effects as BPA, potentially affecting human development and reproductive health.

Body Systems
Cardiovascular Endocrine Nervous Reproductive
Models
Zebrafish
Study Type Review

Recent research has raised concerns about widespread exposure to chemicals that resemble bisphenol A (BPA) structurally or functionally. Because of the strict regulations governing production and use, various bisphenol analogs to replace BPA have increased. Some analogs have been reported to have disruptive physiological and endocrine effects. This study focuses on the impact of bisphenol A analogs on zebrafish embryos. The effect of bisphenol analogs is a major concern, prompting researchers to conduct numerous related studies. Regrettably, previous research has not focused on embryonic health. A systematic search strategy based on the RepOrting Standards for Systematic Evidence Syntheses (ROSES) guidelines was used. Three central journal repositories were used: Scopus, Web of Science, and ScienceDirect. Thirteen articles were discovered through search efforts and will be thoroughly examined. Bisphenol analogs were unearthed to have similar adverse effects on embryonic health as bisphenol-A. This study clarified how bisphenol A analogs affect embryonic development and cytoskeletal organization in the zebrafish model by disrupting the endocrine, cardiovascular, nervous, reproductive, and other systems. To thoroughly investigate these issues, more research on each source, metabolic pathway, exposure mechanisms, and effects on organisms is required.

Read via DOI Download PDF

Share this paper

Post Share Share Pin Email