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Non-destructive biomarkers can reveal effects of the association of microplastics and pharmaceuticals or personal care products

Marine Pollution Bulletin 2022 15 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Letícia Fernanda da Silva, Caio Rodrigues Nobre, Beatriz Barbosa Moreno, Camilo Dias Seabra Pereira, Denis Moledo de Souza Abessa, Rodrigo Brasil Choueri, Paloma Kachel Gusso‐Choueri, Augusto César

Summary

Non-destructive biomarkers in crabs were evaluated to assess the combined effects of microplastics with pharmaceuticals and personal care products, finding measurable biological responses to co-exposure that could be detected without sacrificing the animals. The study demonstrates the utility of non-lethal sampling approaches for monitoring microplastic mixture toxicity in marine invertebrates.

Body Systems

Methods to assess the effects of contaminants on marine organisms typically involve euthanasia to obtain samples, but less invasive techniques may be more appropriate for working with threatened species. In this study, were assessed the biological responses of crabs exposed to microplastics and contaminants of emerging concern. Biochemical and cellular effects (lipid peroxidation, DNA damage, cholinesterase activity, and lysosomal membrane stability) in hemolymph were analyzed in a kinetic study, at 3 and 7 days, in U. cordatus exposed to microplastics spiked with Triclosan (TCS) or 17α-Ethynylestradiol (EE2). The results showed that the contaminants were produced toxic effects in the crabs exposed either to the microplastics alone (oxidative stress, genotoxicity, and neurotoxicity), or to microplastics with TCS or EE2 adsorbed (neurotoxic and cytotoxic). The present study showed the responsiveness of non-lethal analyzes to understanding the biological effects of combined exposure to microplastics and chemical pollution.

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