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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Human Health Effects Policy & Risk Sign in to save

Mixed Contaminants: Occurrence, Interactions, Toxicity, Detection, and Remediation

Molecules 2022 67 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Anirban Goutam Mukherjee, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Uddesh Ramesh Wanjari, Mohamed Ahmed Eladl, Kaviyarasi Renu, Mohamed El‐Sherbiny, Dalia Mahmoud Abdelmonem Elsherbini, Sandra Kannampuzha, Aarthi Sukumar, Sandra Kannampuzha, Aarthi Sukumar, Anirban Goutam Mukherjee, Kaviyarasi Renu, Sandra Kannampuzha, Sandra Kannampuzha, Madurika Ravichandran, Uddesh Ramesh Wanjari, Madurika Ravichandran, Kaviyarasi Renu, Kaviyarasi Renu, Balachandar Vellingiri, Balachandar Vellingiri, Balachandar Vellingiri, Sabariswaran Kandasamy, Abilash Valsala Gopalakrishnan Abilash Valsala Gopalakrishnan Abilash Valsala Gopalakrishnan

Summary

This review examines how mixed environmental contaminants, including microplastics, heavy metals, pesticides, and pharmaceuticals, interact when present together in the environment. The study highlights that pollutant mixtures can produce synergistic toxic effects that are greater than the sum of individual pollutants, making combined contamination a more complex risk than single-pollutant assessments suggest.

Study Type In vivo

The ever-increasing rate of pollution has attracted considerable interest in research. Several anthropogenic activities have diminished soil, air, and water quality and have led to complex chemical pollutants. This review aims to provide a clear idea about the latest and most prevalent pollutants such as heavy metals, PAHs, pesticides, hydrocarbons, and pharmaceuticals-their occurrence in various complex mixtures and how several environmental factors influence their interaction. The mechanism adopted by these contaminants to form the complex mixtures leading to the rise of a new class of contaminants, and thus resulting in severe threats to human health and the environment, has also been exhibited. Additionally, this review provides an in-depth idea of various in vivo, in vitro, and trending biomarkers used for risk assessment and identifies the occurrence of mixed contaminants even at very minute concentrations. Much importance has been given to remediation technologies to understand our current position in handling these contaminants and how the technologies can be improved. This paper aims to create awareness among readers about the most ubiquitous contaminants and how simple ways can be adopted to tackle the same.

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