A One Health Perspective and Introduction

It is generally appreciated that ambient ultrafine particles, and both naturally occurring, and anthropogenic nanoparticles are extraordinarily complex, diverse, and potentially toxic to both the natural environmental and human health. This realization is complemented by an emerging concern in the field of toxicology of the broader environmental, ecotoxicological, and human health impact of an ever-increasing diversity of environmentally persistent engineered nanomaterials and nanoparticles – to include micro- and nanoplastic contaminants. The net impact of nano- and ultrafine particulates on the ecological environment and human health thus fits the evolving paradigm of "One Health" that was first posited by the One Health Initiative Task Force. In logically organized sections of this book, the effects of nanoparticles on aquatic/marine and terrestrial organisms is surveyed across case examples, to include possible mechanisms of action, and emerging issues that are aligned to environmental and ecological nanotoxicology, and of course the "One Health" paradigm. Focused discussions of ultrafine and engineered nanoparticle toxicology, their modification by environmental media, and subsequent health impacts will provide the reader with specific examples of the biology and toxicological outcomes following exposure to nanoparticles. The reader of this book will benefit from a strengthened appreciation of the environmentally dangerous and adverse health impact from exposure to nanoparticles.