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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Sign in to save

Differences in the characteristics and pulmonary toxicity of nano- and micron-sized respirable coal dust

Respiratory Research 2022 17 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 45 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Yinci Zhang, Yinci Zhang, Amin Li, Jiaojiao Liang, Jiaojiao Liang, Niandie Cao, Niandie Cao, Jiafeng Gao, Jiaojiao Liang, Jiafeng Gao, Jiaojiao Liang, Niandie Cao, Niandie Cao, Shuping Zhou, Xiaolong Tang

Summary

Researchers compared how nano-sized versus micron-sized coal dust particles affect lung tissue, finding that the nanosized particles caused more severe inflammation, mitochondrial damage, cell death, and scarring than larger particles. The results suggest particle size is a critical factor in determining how harmful inhaled dust — and by extension, nanoplastics — can be to the respiratory system.

Stimulation with CD-NPs resulted in more pronounced acute and chronic lung toxicity than did stimulation with CD-MPs. These effects included acute inflammatory response, mitochondrial damage, pyroptosis, and necrosis, and more pulmonary fibrosis induced by epithelial-mesenchymal transition.

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