We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Factors promoting and limiting antimicrobial resistance in the environment – Existing knowledge gaps
Summary
This review highlights overlooked factors in antimicrobial resistance dissemination, emphasizing knowledge gaps that must be addressed to create a comprehensive understanding of resistance spread within the One Health framework.
The dissemination of multidrug-resistant bacteria strains and genes carrying antibiotic resistance is currently considered to be one of the most important global problem. The WHO calls for the need to contain the spread of Antimicrobial Resistance (AMR) from all possible sources. There have been many international actions grouping scientists studying this phenomenon, and quite a lot of scientific projects devoted to this problem have already been carried out. As well, so far several strategies have been developed that can inhibit the AMR spread. In this mini-review, we highlight overlooked aspects that seem to be crucial for creating a comprehensive picture of AMR, especially in the context of One Health approach.
Sign in to start a discussion.
More Papers Like This
Antimicrobial and the Resistances in the Environment: Ecological and Health Risks, Influencing Factors, and Mitigation Strategies
This review examines how antimicrobial contamination in the environment contributes to the growing problem of antimicrobial resistance. Researchers found that residual antimicrobials from medical and agricultural use continuously enter ecosystems, promoting the spread of resistant bacteria and resistance genes. The study highlights environmental factors that are often overlooked and discusses strategies for reducing antimicrobial pollution and limiting resistance spread.
The Role of the Environment (Water, Air, Soil) in the Emergence and Dissemination of Antimicrobial Resistance: A One Health Perspective
This review examines how water, soil, and air act as reservoirs for antibiotic-resistant bacteria, with microplastics highlighted as one of several agents that help spread drug-resistant genes across environments. The findings matter for human health because microplastics can carry antibiotic-resistant bacteria from wastewater and agricultural runoff into water supplies and food systems.
Mapping the evidence of the effects of environmental factors on the prevalence of antibiotic resistance in the non-built environment
Researchers conducted a systematic review mapping how environmental factors influence the spread of antibiotic resistance outside of hospitals and farms. They found that factors including temperature, heavy metals, microplastics, and wastewater discharge all contribute to resistance gene prevalence in natural environments. The study underscores the need for a holistic approach that considers environmental conditions alongside antibiotic use when addressing the global resistance crisis.
The Role of Stakeholders’ Understandings in Emerging Antimicrobial Resistance: A One Health Approach
This review examines the growing problem of antimicrobial resistance through a One Health lens, connecting antibiotic misuse in human medicine, veterinary care, and agriculture. Researchers found that how different stakeholder groups understand and respond to antimicrobial resistance varies widely, which complicates coordinated action. The study emphasizes that tackling antibiotic resistance requires collaboration across health, agriculture, and environmental sectors.
Antibiotic Resistance Genes in Food Animal Production: Environmental Implications and One Health Challenges
This review examines how antibiotic use in livestock and aquaculture contributes to the spread of antimicrobial resistance genes across the human-animal-environment interface. Researchers found that a substantial proportion of resistance genes detected in farm environments are shared with those found in human clinical settings. The study emphasizes the need for a One Health approach to surveillance and highlights the role of environmental reservoirs, including those contaminated with microplastics, in disseminating resistance.