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Derivatives of Plastics as Potential Carcinogenic Factors: The Current State of Knowledge
Summary
Researchers reviewed the current evidence on micro- and nanoplastics as potential carcinogenic substances that may cause DNA damage. The review found correlations between exposure to micro- and nanoplastic particles and the onset of several cancers, though the study notes that more research is needed to establish clear causal relationships between plastic particle exposure and cancer development.
Micro- and nanoplatics have been already reported to be potential carcinogenic/mutagenic substances that might cause DNA damage, leading to carcinogenesis. Thus, the effects of micro- and nanoplastics exposure on human health are currently being investigated extensively to establish clear relationships between those substances and health consequences. So far, it has been observed that there exists a definite correlation between exposure to micro- and nanoplastic particles and the onset of several cancers. Therefore, we have conducted research using PubMed, Web of Science, and Scopus databases, searching for all the research papers devoted to cancers that could be potentially related to the subject of exposure to nano- and microplastics. Ultimately, in this paper, we have discussed several cancers, including hepatocellular carcinoma, pancreatic cancer, pancreatic ductal adenocarcinoma, biliary tract cancer, and some endocrine-related cancers.