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Systematic Review ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 1 ? Systematic review or meta-analysis. Synthesizes findings across many studies. Strongest evidence. Human Health Effects Sign in to save

Effects of Nano and Microplastics on the Inflammatory Process: In Vitro and In Vivo Studies Systematic Review

Frontiers in Bioscience-Landmark 2022 54 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Eloise Pulvirenti, Margherita Ferrante, Nunziata Barbera, Claudia Favara, Erica Aquilia, Marco Palella, Antonio Cristaldi, Gea Oliveri Conti, Maria Fiore

Summary

This systematic review examined both lab-based and animal studies on how micro- and nanoplastics trigger inflammation in the body. The evidence supports a link between microplastic exposure and inflammatory responses, which are involved in many chronic diseases. While more high-quality studies are needed — especially on nanoplastics — the findings suggest that plastic particles may contribute to ongoing low-level inflammation in exposed organisms.

Body Systems
Immune
Study Type Review

This systematic review seems to support the relationship between the exposure to MPs and the inflammatory processboth in vivo and in vitro. Greater caution is needed about the role of NPs because ofa very small number of studies. Additional high-quality studies are warranted to confirm these results, especially the research should be focused on NPs being lacking literature.

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