We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
The fetal exposome and preterm birth: a systematic synthesis of environmental exposures and multi-omics evidence
Summary
This systematic review integrates fetal exposome concepts with multi-omics data on preterm birth risk, concluding that combining exposure measurement with biomarker discovery may support precision-guided prenatal interventions, though standardized methodologies and equitable implementation remain challenges.
Integrating fetal exposome concepts with multi-omics enhances mechanistic insight into PTB risk and may support biomarker discovery and precision-guided prenatal interventions. Clinical translation requires standardized exposure measurement, biomarker validation, and equity-focused implementation.
Sign in to start a discussion.
More Papers Like This
Placental Micro- and Nanoplastic Contamination: A Systematic Review of Eco-Exposome Pathways to Preterm Birth and Neonatal Outcomes
This systematic review examined evidence that micro- and nanoplastics have been found in human placentas and may be linked to preterm birth. The particles appear to cause inflammation, oxidative stress, and disruption of placental function through multiple molecular pathways, raising concerns about the impact of plastic pollution on pregnancy outcomes and newborn health.
Exposomics as a discovery engine: a systematic scoping review of emerging environmental contaminants and novel biological effects
This scoping review mapped how exposomics tools—including high-resolution mass spectrometry, multi-omics integration, and wearable sensors—have been applied over the past decade to discover novel environmental contaminant exposures and their health effects. It found emerging contaminants like microplastics and PFAS increasingly captured by non-targeted approaches.
Exposomics as a discovery engine for emerging contaminants and hidden biological risks
This review examined how exposomics—the science of comprehensively characterizing all chemical exposures an individual encounters—has matured into a practical discovery tool for identifying emerging contaminants and hidden health risks. The authors found that high-resolution mass spectrometry combined with multi-omics and wearable sensors can uncover chemical exposures missed by conventional targeted monitoring.
Integrative Biochemical Diagnostics: From Prenatal Genomics to Environmental and Behavioral Biomarkers
This short review proposes an integrative diagnostic framework linking advances in prenatal genomics, metabolic biomarkers, and environmental sensing, including detection of microplastics and endocrine-disrupting chemicals as emerging biomarkers of health risk.
Integrative Biochemical Diagnostics: From Prenatal Genomics to Environmental and Behavioral Biomarkers
This short review proposes an integrative diagnostic framework linking advances in prenatal genomics, metabolic biomarkers, and environmental sensing, including detection of microplastics and endocrine-disrupting chemicals as emerging biomarkers of health risk.