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Evidence on Invasion of Blood, Adipose Tissues, Nervous System and Reproductive System of Mice After a Single Oral Exposure: Nanoplastics versus Microplastics.

PubMed 2022 62 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Rui Zhang, Rui Zhang, Zuo Sen Yang, Zuo Sen Yang, Rui Zhang, Ying Long Bai, Rui Zhang, Wei Sun, Ying Long Bai, Jun Na, Cui Hong Jin, Cui Hong Jin, Jun Na, Jun Na, Jun Na, Cui Hong Jin, Rui Zhang, Rui Zhang, Cui Hong Jin, Yuan Gao, Ying Long Bai, Ying Long Bai, Jun Na, Jun Na, Guo Wei Pan, Guo Wei Pan, Ling Jun Yan Ling Jun Yan, Yuan Gao, Wei Sun, Guo Wei Pan, Guo Wei Pan, Zuo Sen Yang, Zuo Sen Yang, Ling Jun Yan, Ling Jun Yan

Summary

Researchers found that after a single oral exposure in mice, nanoplastics were rapidly absorbed into the blood, accumulated in fat tissues, and crossed both the blood-brain and blood-testis barriers. The study demonstrated that the distribution and behavior of plastic particles in mammals is strongly dependent on particle size, with nanoplastics showing substantially greater tissue penetration than microplastics.

Body Systems

Nervous Reproductive

Models

Mouse

After a single oral exposure, NPs are absorbed rapidly in the blood, accumulate in adipose tissues, and penetrate the blood-brain/testis barriers. As expected, the toxicokinetics of MPs is significantly size-dependent in mammals.

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