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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Reproductive & Development Sign in to save

Evidence on Invasion of Blood, Adipose Tissues, Nervous System and Reproductive System of Mice After a Single Oral Exposure: Nanoplastics versus Microplastics.

PubMed 2022 62 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Zuo Sen Yang, Ying Long Bai, Cui Hong Jin, Jun Na, Rui Zhang, Yuan Gao, Guo Wei Pan, Ling Jun Yan, Wei Sun

Summary

Researchers found that after a single oral exposure in mice, nanoplastics were rapidly absorbed into the blood, accumulated in fat tissues, and crossed both the blood-brain and blood-testis barriers. The study demonstrated that the distribution and behavior of plastic particles in mammals is strongly dependent on particle size, with nanoplastics showing substantially greater tissue penetration than microplastics.

Body Systems
Nervous Reproductive
Models
Mouse

After a single oral exposure, NPs are absorbed rapidly in the blood, accumulate in adipose tissues, and penetrate the blood-brain/testis barriers. As expected, the toxicokinetics of MPs is significantly size-dependent in mammals.

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