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Emergence of Early Clue to Neurodegenerative Diseases Induced in Immature Mice by Combined Exposure to Polypropylene Microplastics and Dehp and the Underlying Molecular Mechanism
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Early clues and molecular mechanism involved in neurodegenerative diseases induced in immature mice by combined exposure to polypropylene microplastics and DEHP
Researchers exposed young mice to polypropylene microplastics combined with DEHP, a chemical commonly found in plastics, and observed significant brain damage including memory problems and damage to the hippocampus. The combined exposure was worse than either substance alone, showing additive or synergistic toxic effects on the developing brain. This is particularly concerning for young children, who are most commonly exposed to polypropylene products and may be more vulnerable to these neurotoxic effects.
Elucidating the Neurotoxicopathological Impact of Micro and Nanoplastics: Mechanistic Insights Into Oxidative Stress-mediated Neurodegeneration and Implications for Public Health in a Plastic Pervasive Era
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