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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Nanoplastics Remediation Sign in to save

Nanoplastics promote the dissemination of antibiotic resistance through conjugative gene transfer: implications from oxidative stress and gene expression

Environmental Science Nano 2023 24 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Xiaowei Liu, Rongrong Xu, Heyang Wu, Kai-Wen Xu, Wenjing Zhang, Zongyu Wang, Wenwen Gong

Summary

Sulfate-modified polystyrene nanoplastics were found to facilitate the conjugative transfer of antibiotic resistance genes between E. coli strains more effectively than larger particles, operating through SOS response induction, increased membrane permeability, and altered gene expression. The findings highlight nanoplastics as potential accelerators of antibiotic resistance spread in the environment.

S-PSNPs facilitated conjugative transfer frequency of ARGs between E. coli strains than L-PSNPs, and the mechanisms include SOS response, membrane permeability and altered related gene expression.

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