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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Reproductive & Development
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Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway
BMC Women s Health
2023
36 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 50
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Pingping Sun,
Yuemin Zhang,
Li-Lan Sun,
Na Sun,
Jinguang Wang,
Hua-Gang Ma
Summary
Researchers found that kisspeptin, a signaling protein, improves the health of ovarian cells in polycystic ovary syndrome (PCOS) by activating PI3K/AKT and ERK cell survival pathways, which reduces cell death and oxidative stress. This points to kisspeptin as a potential therapeutic target for managing PCOS-related infertility.
Kisspeptin improves proliferation and alleviates apoptosis and oxidative stress in ovarian granulosa cells by activating PI3K/AKT and ERK signalling.