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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Nanoplastics Sign in to save

Iodine-131 radiolabeled polyvinylchloride: A potential radiotracer for micro and nanoplastics bioaccumulation and biodistribution study in organisms

Marine Pollution Bulletin 2023 22 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Miftakul Munir, Heny Suseno Miftakul Munir, Umi Nur Sholikhah, Moch Subechi, Moch Subechi, Heny Suseno Miftakul Munir, Ahid Nurmanjaya, Heny Suseno Enny Lestari, Heny Suseno Heny Suseno Heny Suseno Enny Lestari, Miftakul Munir, Anung Pujiyanto, Moch Subechi, Moch Subechi, Kukuh Eka Prasetya, Moch Subechi, Moch Subechi, Miftakul Munir, Moch Subechi, Moch Subechi, Kukuh Eka Prasetya, Anung Pujiyanto, Kukuh Eka Prasetya, Kukuh Eka Prasetya, Anung Pujiyanto, Miftakul Munir, Ahid Nurmanjaya, Yanto Yanto, Yanto Yanto, Miftakul Munir, Miftakul Munir, Miftakul Munir, Daya Agung Sarwono, Daya Agung Sarwono, Yanto Yanto, Heny Suseno Yanto Yanto, Anung Pujiyanto, Moch Subechi, Moch Subechi, Moch Subechi, Moch Subechi, Heny Suseno Daya Agung Sarwono, Daya Agung Sarwono, Heny Suseno

Summary

Researchers developed a method to radiolabel polyvinyl chloride with iodine-131 for use as a radiotracer to study microplastic bioaccumulation and biodistribution in organisms. The study demonstrated successful preparation of radiolabeled PVC particles, offering a highly sensitive nuclear technique for tracking the fate of micro- and nanoplastics in biological systems.

Polymers
PVC

The microplastics amount in the environment is significantly increasing due to human activity, and the hazards are still being investigated. To evaluate the fate of microplastics in organisms, an accurate, fast, and sensitive method is required. Nuclear technology harnessing radiotracer is one of the most sensitive and accurate method for bioaccumulation, biodistribution and biokinetic study. Here, we developed a preparation method for radioiodinated polyvinyl chloride (PVC) as a potential radiotracer of microplastics. Iodine-131 (<sup>131</sup>I) as a potential radiotracer for microplastic was used in this experiment (activity of 98.05-221.63 MBq). The <sup>131</sup>I-PVC was prepared using the Conant-Finkelstein reaction with a solvent combination of phosphate buffer (B), acetone (A), and tetrahydrofuran (T). Such preparation method resulted in spherical <sup>131</sup>I-PVC with sizes ranging from 608.6 to 5457.0 nm. Our study showed that acetone is the most suitable solvent for the radioiodination process, resulting in a stable <sup>131</sup>I-PVC for up to six days.

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