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Research Progress on the Correlation between Environmental Phthalate Exposure and Thyroid Hormone Level
Summary
This review examines how phthalate plasticizers — widely used in food packaging, toys, and medical supplies — disrupt thyroid hormone levels after environmental release, drawing on epidemiological and toxicological evidence linking phthalate exposure to thyroid dysfunction. The findings highlight phthalates as endocrine-disrupting chemicals with significant public health implications.
Environmental phthalates are frequently used in toys, food packaging, medical supplies, and other plastic goods. Because they are easily released from plastics, they might be a concern to the natural system and public health. This study focuses on the impact of phthalate esters, a widely used plasticizer, on the environment and its relationship with human thyroid hormones. As environmental endocrine disruptors, phthalates can destroy the stability of ecosystems and lead to changes in their functions, thus posing a potential threat to ecosystem health and biodiversity. In addition, phthalates may also have adverse effects on thyroid tissue and function, increasing the risk of thyroid diseases. Therefore, it is very important to strengthen the management and supervision of phthalate esters to ensure the safety of ecosystem and human health. The results of this research can provide scientific basis for evaluating the potential health risks of phthalate esters exposure, and can also provide reference for the implementation of future environmental policies and health management strategies.