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A Review on Tetrabromobisphenol A: Human Biomonitoring, Toxicity, Detection and Treatment in the Environment
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This review summarizes the current evidence on tetrabromobisphenol A (TBBPA), a flame retardant chemical found in consumer products that acts as an endocrine disruptor. Researchers compiled findings on how TBBPA has been detected in human samples and various environments, along with its toxic effects on hormone systems. The review highlights that research on TBBPA exposure routes, detection methods, and treatment technologies is still in early stages and needs further development.
Tetrabromobisphenol A (TBBPA) is a known endocrine disruptor employed in a range of consumer products and has been predominantly found in different environments through industrial processes and in human samples. In this review, we aimed to summarize published scientific evidence on human biomonitoring, toxic effects and mode of action of TBBPA in humans. Interestingly, an overview of various pretreatment methods, emerging detection methods, and treatment methods was elucidated. Studies on exposure routes in humans, a combination of detection methods, adsorbent-based treatments and degradation of TBBPA are in the preliminary phase and have several limitations. Therefore, in-depth studies on these subjects should be considered to enhance the accurate body load of non-invasive matrix, external exposure levels, optimal design of combined detection techniques, and degrading technology of TBBPA. Overall, this review will improve the scientific comprehension of TBBPA in humans as well as the environment, and the breakthrough for treating waste products containing TBBPA.
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Association of tetrabromobisphenol A (TBBPA) with micro/nano-plastics: A review of recent findings on ecotoxicological and health impacts
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This review examines how tetrabromobisphenol A (TBBPA), a widely used flame retardant found in plastic products, binds to micro and nanoplastics in the environment. When TBBPA hitches a ride on microplastics, the combined effect on organisms and ecosystems is often worse than either contaminant alone. Since TBBPA is an additive in many plastic products, the findings highlight how microplastics can carry harmful chemicals directly into the body.
Effects of TBBPA Exposure on Neurodevelopment and Behavior in Mice
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This study found that perinatal exposure to the flame retardant TBBPA at environmentally relevant doses impaired neurodevelopment in mice, with male offspring showing deficits in motor function, memory, and social interaction, and females showing motor impairment, accompanied by changes in gene expression linked to behavioral abnormalities.
Sorption of tetrabromobisphenol A onto microplastics: Behavior, mechanisms, and the effects of sorbent and environmental factors
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The sorption of the flame retardant tetrabromobisphenol-A (TBBPA) onto four types of microplastics — polyethylene, polypropylene, polystyrene, and polyvinyl chloride — was studied in aqueous environments. Results revealed that polymer type, surface area, and hydrophobic interactions were key factors controlling how much TBBPA accumulates on microplastic surfaces.
Tetrabromobisphenol A (TBBPA) degradation in anaerobic biosystems: from bioengineering to meta-omics
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Researchers investigated the anaerobic biodegradation of tetrabromobisphenol A (TBBPA), a brominated flame retardant used in plastics and electronics, through a series of bioengineering and meta-omics experiments, developing sensitive analytical methods and characterizing the microbial communities responsible for reductive debromination to improve treatment of TBBPA-contaminated effluents.
Tetrabromobisphenol A (TBBPA) generation and removal paths analysis in printed circuit board (PCB) industrial wastewater: Lab-scale investigations
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This study analyzed the generation and removal pathways of tetrabromobisphenol A (TBBPA) in industrial wastewater from printed circuit board manufacturing. Lab-scale experiments characterized TBBPA sources and its fate in wastewater treatment processes.
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