Back to papers
0
Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Sign in to save

Current Evidence on Bisphenol A Exposure and the Molecular Mechanism Involved in Related Pathological Conditions

Pharmaceutics 2023 27 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Ylenia Della Rocca, Enrico Matteo Traini, Francesca Diomede, Luigia Fonticoli, Oriana Trubiani, Alessia Paganelli, Jacopo Pizzicannella, Guya Diletta Marconi

Summary

This review examines the molecular mechanisms by which bisphenol A (BPA), a common endocrine-disrupting chemical found in plastics, may contribute to various health conditions. Researchers analyzed BPA's effects on mesenchymal stem cells and fat cell development, as well as its uses in dental, orthopedic, and industrial applications. The study suggests that BPA exposure can alter multiple molecular pathways involved in immune, metabolic, and cellular processes.

Body Systems
Cardiovascular Endocrine Immune

Bisphenol A (BPA) is one of the so-called endocrine disrupting chemicals (EDCs) and is thought to be involved in the pathogenesis of different morbid conditions: immune-mediated disorders, type-2 diabetes mellitus, cardiovascular diseases, and cancer. The purpose of this review is to analyze the mechanism of action of bisphenol A, with a special focus on mesenchymal stromal/stem cells (MSCs) and adipogenesis. Its uses will be assessed in various fields: dental, orthopedic, and industrial. The different pathological or physiological conditions altered by BPA and the related molecular pathways will be taken into consideration.

Read via DOI Download PDF

Share this paper

Post Share Share Pin Email