Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp.

Mousumi Bhattacharyya; Rinita Dhar; Suman Basu; A. Das; Darren M. Reynolds; Tapan K. Dutta

doi:10.1186/s12934-023-02096-0

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Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp.

Microbial Cell Factories 2023 17 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.

Mousumi Bhattacharyya, Rinita Dhar, Suman Basu, A. Das, Darren M. Reynolds, Tapan K. Dutta

Summary

Biochemical, genomic, and transcriptomic analyses revealed the metabolic pathways used by Mycolicibacterium sp. strain MBM to degrade the plasticizer di(2-ethylhexyl) phthalate, with the bacterium functioning in both freshwater and seawater salinity ranges.

Body Systems

Endocrine

Study Type Environmental

A detailed co-relation of biochemical, genomic, transcriptomic and RT-qPCR analyses highlights the PAE-degrading catabolic machineries in strain MBM. Further, due to functional attributes in the salinity range of both freshwater and seawater, strain MBM may find use as a suitable candidate in the bioremediation of PAEs.

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