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Atmospheric microplastic and nanoplastic: The toxicological paradigm on the cellular system
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This review examines how airborne microplastics and nanoplastics affect human cells after being inhaled into the lungs. Because these particles are tiny and lightweight, they can penetrate deep into lung tissue and potentially enter the bloodstream. Studies on human cell lines show that inhaled plastic particles can cause inflammation, oxidative stress, and DNA damage, raising concerns about long-term respiratory and systemic health effects.
The increasing demand for plastic in our daily lives has led to global plastic pollution. The improper disposal of plastic has resulted in a massive amount of atmospheric microplastics (MPs), which has further resulted in the production of atmospheric nanoplastics (NPs). Because of its intimate relationship with the environment and human health, microplastic and nanoplastic contamination is becoming a problem. Because microplastics and nanoplastics are microscopic and light, they may penetrate deep into the human lungs. Despite several studies demonstrating the abundance of microplastics and nanoplastics in the air, the potential risks of atmospheric microplastics and nanoplastics remain unknown. Because of its small size, atmospheric nanoplastic characterization has presented significant challenges. This paper describes sampling and characterization procedures for atmospheric microplastics and nanoplastics. This study also examines the numerous harmful effects of plastic particles on human health and other species. There is a significant void in research on the toxicity of airborne microplastics and nanoplastics upon inhalation, which has significant toxicological potential in the future. Further study is needed to determine the influence of microplastic and nanoplastic on pulmonary diseases.
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Airborne microplastics: A narrative review of potential effects on the human respiratory system
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This review consolidates research on airborne microplastics and their potential effects on the human respiratory system. Studies show that inhaled microplastics can deposit in the lungs, trigger inflammation, cause oxidative stress, and lead to cell damage and death. While human exposure evidence is still limited, animal and cell studies suggest that long-term inhalation of airborne microplastics could pose significant risks to lung health.
Cellular Impact of Micro(nano)plastics on Human Health: A Review.
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This review examined how micro(nano)plastics (MNPs) entering the human body through ingestion, inhalation, and skin contact affect cells and tissues. It synthesized evidence of oxidative stress, inflammation, DNA damage, and endocrine disruption associated with MNP exposure.
Cytotoxic Effects of Microplastics on Human Cells
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This study reviewed and tested the cytotoxic effects of microplastics on human cells, finding that microplastic particles can cause cell damage, inflammation, and oxidative stress at relevant concentrations. The results support growing concern that microplastics ingested or inhaled by humans may pose direct health risks at the cellular level.
Inhaled Microplastics as Emerging Respiratory Toxicants: From Cellular Mechanisms to Global Health Policy
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This review pulls together a decade of research on tiny plastic particles floating in the air we breathe, finding that once inhaled, they can trigger inflammation, cell damage, and immune disruption deep in the lungs, effects linked to conditions like asthma, COPD, and even lung cancer. The risk may be even greater since these particles often carry other harmful substances like heavy metals along for the ride. That said, scientists still lack standardized ways to measure this exposure, so more consistent research is needed before we fully understand how worried we should be, but it's a good reason to pay attention to air quality and plastic pollution in daily life.
Airborne microplastics and their impact on human health: A critical review
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This review analyzes the growing body of research on microplastics floating in indoor and outdoor air and their potential effects on human health. Evidence indicates that inhaled microplastics can trigger inflammatory responses and cellular damage in the lungs, liver, and reproductive system, and may carry toxic additives deeper into the body. The authors call for more interdisciplinary research to understand the long-term health implications of breathing in these tiny plastic particles.
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