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Environmental nanoparticles and placental research
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This short piece highlights that nanoparticles — specifically particulate black carbon and nanoplastics — are small enough to cross placental barriers, raising concern about fetal exposure during pregnancy. It underscores nanoplastics as an emerging area of placental research with potential implications for fetal development.
Nanoparticles (NP) (usually understood as in the range 1-100nm) are, in principle, capable of intercellular barrier penetration as well as ingestion by cells, particularly phagocytes and transporting epithelia.Here we focus on particulate black carbon (BC) and nanoplastics.
More Papers Like This
Environmental nanoparticles and placental research
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This commentary reviews how nanoparticles — including nanoplastics and black carbon from combustion — can potentially cross the placental barrier and reach the developing fetus. The authors highlight early evidence linking microplastic and nanoparticle exposure to adverse pregnancy outcomes, and call for better detection methods and controlled studies to understand the true risk to fetal development.
Biological interactions between nanomaterials and placental development and function following oral exposure
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Researchers reviewed animal studies on orally ingested nanomaterials (including nanoplastics) and found that while the placenta is generally an effective barrier preventing fetal transfer, nanomaterials accumulating in placental tissue can impair placental development and function, with potential downstream effects on fetal health.
Placental Exposure to Nanoplastics Threatening the Maternal and Fetal Health
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This review examines how nanoplastics reaching the placenta threaten maternal and fetal health, summarizing evidence from animal and in vitro studies showing that placental nanoplastic accumulation disrupts nutrient transport, immune function, and fetal development.
Breach of Security? Placental Uptake of Micro- and Nanoplastic Particles
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This review examines emerging evidence for placental uptake of micro- and nanoplastic particles, exploring whether the placenta's barrier function can be breached by these contaminants during pregnancy. The review raises concerns about potential fetal exposure to plastic particles and the implications for developmental health.
A Systematic Review of the Placental Translocation of Micro- and Nanoplastics
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Nine out of eleven studies confirmed that micro- and nanoplastics can cross the placental barrier, with translocation depending on particle size, charge, chemical modification, and protein corona formation. Animal and in vitro studies showed emerging evidence of placental and fetal toxicity from plastic particle exposure.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.