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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Remediation Sign in to save

Isothermal calorimetry calscreener in the metabolism gauge of human malignant neoplastic cells: a burgeoning nexus in cancer biochemical metrology and diagnostics

Bulletin of the National Research Centre/Bulletin of the National Research Center 2023 4 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 45 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Michael Tosin Bayode, Mercy Adewumi Alabi, Tope Abraham Ibisanmi, Ayomide Faith Okiti, Olabisi Omowumi Adebisi, Olabisi Omowumi Adebisi, Philemon Olayemi Aro, Philemon Olayemi Aro, Ayoola Emmanuel Awode, Oyindamola Sukurat Lawal, Oyindamola Sukurat Lawal, Olamide Joshua Babatunde, Gladys Oluwafisayo Adenikinju

Summary

This study examined the potential of isothermal microcalorimetry (IMC) using a calscreener instrument to detect metabolic alterations in cancer cells, proposing it as a diagnostic tool for cancer biochemical metrology. The review discusses technical requirements for accurate IMC measurements and positions the calscreener as a complementary approach to existing cancer screening methods.

Abstract Background At present, the function of isothermal microcalorimetry (IMC) calscreener in detecting alterations in the metabolic pathways of cancer cells remains unexplored. We disclosed the shortcomings of current screening methods and the need for precise and dependable instruments in the detection and informed treatment of cancer via the IMC in relation to the experimental procedures required to obtain accurate results. Main body of abstract We examined the intricate technical aspects of isothermal calorimetry. The application of the IMC calscreener in cancer research is then discussed in depth, including how it can be used to evaluate the efficacy of treatments, identify metabolic inhibitors, and assess metabolic rates. We also investigated the diagnostic potential of isothermal calorimetry, particularly for early cancer detection and tracing therapy efficacy. Conclusions General findings shed light on the present issues and potential approaches for isothermal calorimetry application in cancer research and diagnosis. We underline the potential for isothermal calorimetry to fundamentally alter how to understand and treat cancer, as well as the need for additional studies to maximize its application in clinical settings. This in turn offers a thorough and fascinating account of the emerging relationship between isothermal calorimetry and cancer biochemistry, as well as its potential to revolutionize cancer detection and therapy.

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