We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Efficient Biorefinery Based on Designed Lignocellulosic Substrate for Lactic Acid Production
Summary
Researchers developed a simultaneous saccharification and fermentation (SSF) process using Celluclast 1.5L enzyme to produce L-lactic acid from brewer's spent grain, achieving 53.1 g/L optically pure product with a volumetric productivity of 3.65 g/L/h without nutrient supplementation. The approach overcomes glucose-induced carbon catabolite repression by co-utilizing pentose and hexose sugars from lignocellulosic biomass.
The current study investigated the feasibility of developing and adopting a few state-of-the-art fermentation techniques to maximize the efficiency of the lignocellulosic waste bioconversion. There have been various efforts towards utilizing the fermentable sugars released from the specific parts of lignocellulose, i.e., cellulose and hemicellulose. However, complete utilization of carbon sources derived from lignocellulosic biomass remains challenging owing to the generated glucose in the presence of β-glucosidase, which is known as glucose-induced carbon catabolite repression (CCR). To overcome this obstacle, a novel simultaneous saccharification and fermentation (SSF) of lactic acid was designed by using Celluclast 1.5L as a hydrolytic enzyme to optimize the generation and utilization of pentose and hexose. Under the optimal enzyme loading and pH condition, 53.1 g/L optically pure L-lactic acid with a maximum volumetric productivity of 3.65 g/L/h was achieved during the SSF from the brewer’s spent grain without any nutrient supplementation. This study demonstrated the potential of lactic acid production from the designed lignocellulosic substrate.
Sign in to start a discussion.
More Papers Like This
Application of an oxidative-biological treatment strategy for production of lactic acid and biomass from vinasse of sugarcane bioethanol industry
Researchers evaluated lactic acid and biomass production from vinasse, a sugarcane bioethanol byproduct, by cultivating Lactococcus lactis strains on ozone- and air-pretreated vinasse at concentrations of 0-33% v/v. The study found that oxidative pretreatment reduced inhibitory compounds, enabling viable microbial growth and lactic acid yields from this high-strength organic waste stream.
Development of a Strategy for L-Lactic Acid Production by Rhizopus oryzae Using Zizania latifolia Waste and Cane Molasses as Carbon Sources
This paper is not about microplastics; it develops a fermentation strategy using food-processing waste (Zizania latifolia residues and cane molasses) as carbon sources to produce L-lactic acid, a precursor for biodegradable polylactic acid plastic.
Unveiling the mechanisms of medium-chain fatty acid production from waste activated sludge alkaline fermentation liquor through physiological, thermodynamic and metagenomic investigations
Researchers investigated converting waste activated sludge fermentation liquor into medium-chain fatty acids (valuable biochemicals) through chain elongation with ethanol as an electron donor, finding optimal selectivity at a 1:1 electron donor-to-acceptor ratio, and identifying Clostridium species as the key microbial drivers using metagenomic analysis — demonstrating a promising pathway for simultaneously treating sewage sludge and producing bio-based chemicals.
Conversion of lignocellulose residue obtained from biorefinery stream to electricity by microbial fuel cell
This review explores using microbial fuel cells (MFCs) to generate electricity from the organic waste left over after lignocellulose biorefinery processes. While focused on bioenergy, the circular economy approach discussed is relevant to reducing industrial waste streams that could otherwise contribute to environmental pollution.
High-performance biodegradable poly(lactic acid) composites with xylan and lignin copolymer
Researchers developed high-performance biodegradable poly(lactic acid) composites by incorporating xylan and lignin derived from lignocellulosic biomass, improving PLA mechanical properties and addressing its brittleness limitations while maintaining biodegradability as a sustainable alternative to conventional plastics.