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Development and efficacy assessment of hand sanitizers and polylactic acid films incorporating caffeic acid and vanillin for enhanced antiviral properties against HCoV-229E

Virology Journal 2023 1 citation ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 30 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Seok‐Woo Hyun, Seok‐Woo Hyun, Sangha Han, Jeong Won Son, Jeong Won Son, Min Su Song, Min Su Song, Dan Ah Kim, Dan Ah Kim, Sang‐Do Ha Sang‐Do Ha

Summary

Researchers developed hand sanitizers and biodegradable polylactic acid (PLA) films — a type of plastic made from plant sugars — infused with caffeic acid and vanillin to fight a coronavirus called HCoV-229E, finding both formulations effectively inactivated the virus. The study also found that organic matter on skin reduces the antiviral effectiveness, recommending that skin be cleaned before applying these products.

This study revealed that caffeic acid and vanillin can be effectively used to control HCoV-229E for hand sanitizers and antiviral films. In addition, it is recommended to remove organic matter from the skin for maintaining the antiviral activity of hand sanitizer and antiviral film as the antiviral activity decreased as the organic load increased in this study.

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