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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Policy & Risk
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Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts
Stem Cells International
2023
14 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 50
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Hongxu Lu,
Zhaoxia Zhang,
Zhaoying Wang,
Jinkui Wang,
Tao Mi,
Liming Jin,
Xin Wu,
Junyi Luo,
Yimeng Liu,
Junhong Liu,
Wenquan Cai,
Peng Guo,
Dawei He
Summary
Researchers found that exosome-mimetic vesicles derived from human mesenchymal stem cells can help protect bone-forming cells from glucocorticoid-induced programmed cell death. The study suggests these vesicles work by regulating the MAPK signaling pathway and reducing reactive oxygen species levels in laboratory experiments.
Body Systems
Our study confirmed that hucMSC-EMVs regulates MAPK-signaling pathway and ROS levels to inhibit DEX-induced osteoblast apoptosis.
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