Comparative in vivo PET/CT, biodistribution, and excretion study of Cu-64 labeled Polypropylene (PP) nanoplastics via various administration routes in mice

PET Tracing of Biodistribution for Orally Administered 64Cu-Labeled Polystyrene in Mice

AI summary · Read the abstract

Researchers used PET imaging to track the real-time biodistribution of orally administered radiolabeled polystyrene microplastics in mice. The study found that microplastics were absorbed from the gastrointestinal tract and distributed to various organs, providing direct visual evidence of how ingested plastic particles can travel through the body.

Comparison of PET tracing and biodistribution between 64Cu-labeled micro-and nano-polystyrene in a murine inhalation model

AI summary · Read the abstract

Using radioactive copper labeling and PET imaging, researchers tracked where inhaled micro- and nano-sized polystyrene particles travel in the body, finding that nanoplastics distributed more widely to organs than microplastics after lung exposure. This is significant for understanding the health risks of airborne plastic particles, which people inhale daily from synthetic textiles, dust, and urban air.

Imaging and quantifying the biological uptake and distribution of nanoplastics using a dual-functional model material

AI summary · Read the abstract

This study used advanced imaging techniques to visualize and quantify nanoplastic uptake and distribution in biological systems, tracking particle translocation from exposure routes into tissues and characterizing intracellular localization.

The distribution of nano- and microplastics in the human body: a Hybrid Perfusion-Diffusion based PBK model

Biodistribution of nanoplastics in mice: advancing analytical techniques using metal-doped plastics

AI summary · Read the abstract

Researchers developed a new analytical method using palladium-doped nanoplastics to track where plastic particles go in the body after ingestion in mice. They found that after short-term exposure, most particles passed through the digestive system and were excreted, but longer-term exposure led to accumulation in body tissues. The study advances the ability to detect and trace nanoplastics at extremely small concentrations in biological samples.