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Mechanisms of Pollution Tolerance in Aquatic Organisms

2025
Patrick Omoregie Isibor, Alex Ajeh Enuneku, Geetha Devi

Summary

This review examined how aquatic organisms tolerate pollution from heavy metals, organic compounds, and emerging contaminants such as microplastics, focusing on molecular, biochemical, and physiological adaptation strategies. Detoxification pathways including antioxidant responses and metallothionein induction were identified as central mechanisms.

Organisms that live in aquatic environments have developed various tolerance mechanisms at the molecular as well as biochemical and physiological levels, which help them exist in polluted habitats. Pollutant-triggered adaptive responses occur because of exposure to heavy metals together with organic compounds as well as emerging contaminants that feature microplastics and pharmaceuticals. Detoxification pathways such as cytochrome P450 systems become active while antioxidants increase to remedy oxidative stress, toxicants are bound by metallothioneins and heat shock proteins, and aquatic organisms modify their behavior to decrease exposure. Membrane transporters together with efflux pumps prevent poisonous substances from building up within cells and genomic together with epigenetic modifications to enable long-term resistance. The modifications shown by organisms differ based on species type as well as age and previous chemical contact exposure, which impacts both food chain dynamics and ecological sustainability. Understanding how organisms develop resistance to pollution is vital for forecasting how species will respond to environmental dangers as well as creating better ecological evaluation procedures and managing pollution impacts in water ecosystems.

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