Environmental bisphenol A exposure triggers trained immunity-related pathways in monocytes

Summary

Researchers discovered that environmental exposure to bisphenol A, a chemical commonly found in plastics, can trigger a process called trained immunity in human immune cells from healthy individuals. This means that even after the chemical is removed, the immune cells remain in a heightened state of activation, which could contribute to chronic inflammation. The study is among the first to show that a plastic-derived compound can reprogram the immune system in this lasting way.