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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
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Icariin improves cardiac function and remodeling via the TGF-β1/Smad signaling pathway in rats following myocardial infarction
European journal of medical research
2023
19 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 45
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Ji Dong Jia,
Ji Dong Jia,
Xing-an Zhao,
Xing-an Zhao,
Siming Tao,
Siming Tao,
Junwen Wang,
R Zhang,
R Zhang,
Hualei Dai,
Hualei Dai,
Xin-jin Zhang,
Xin-jin Zhang,
Han Ming-hua,
Han Ming-hua,
Bei Yang,
Yu Li,
Jintao Li
Summary
This paper is not about microplastic pollution. It studies the effects of icariin, a plant-derived compound, on cardiac function and tissue remodeling in rats after heart attacks, finding that it works through the TGF-beta1/Smad signaling pathway.
Body Systems
Models
In an experimental rat model of MI, the administration of icariin resulted in the amelioration of both cardiac function and remodeling processes, operating through the intricate TGF-β1/Smad signaling pathway.
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