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Variability of bile bacterial profiles and drug resistance in patients with choledocholithiasis combined with biliary tract infection: a retrospective study
Summary
This retrospective study examined changing patterns of bacterial infections in bile from patients with bile duct stones and biliary tract infections. Researchers found that gram-positive bacterial infections have been increasing over time, while gram-negative bacteria including E. coli have become less common. The findings suggest that antibiotic treatment for these infections should be tailored to reflect current local bacterial profiles.
A significant change has occurred in the bile bacterial spectrum in patients with choledocholithiasis and biliary tract infection. The incidence of gram-positive cocci infections has increased annually, while that of gram-negative bacilli and E. coli infections has decreased. Antibiotic administration should be tailored based on the local bacterial profile.