0
Systematic Review ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 1 ? Systematic review or meta-analysis. Synthesizes findings across many studies. Strongest evidence. Environmental Sources Human Health Effects Sign in to save

Neurotoxicity of microplastic particles in the human brain: a systematic review

Turkish Neurosurgery 2024 Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Sait Kayhan, Esra Şafak Yılmaz, Özkan Tehli, Yusuf İzci

Summary

This systematic review examines how microplastic particles may affect the human brain and nervous system. The research found that microplastics can reach the brain and cause changes in behavior and thinking, though more studies are needed to understand the long-term effects. This is an early but important signal that plastic pollution could impact brain health.

Body Systems
Study Type Review

MPs are a significant global health problem. With the widespread use and accumulation of plastic materials, MPs can reach the nervous system and exert neurotoxic effects manifesting in behavioral and cognitive changes. The current evidence is insufficient to delineate the possible long-term outcomes of MP exposure. Further clinical studies are warranted to elucidate the mechanisms underlying these neurotoxic effects.

Sign in to start a discussion.

More Papers Like This

Article Tier 2

Impact of micro- and nanoplastics exposure on human health: focus on neurological effects from ingestion

This review compiles emerging evidence on how ingested microplastics and nanoplastics may affect the brain and nervous system. Researchers found that these particles can disrupt gut bacteria, cross the blood-brain barrier, and accumulate in neural tissue, potentially triggering inflammation, oxidative stress, and protein changes linked to cognitive problems. The study highlights an urgent need for more human research, as initial findings have associated elevated plastic particle levels in brain tissue with neurological concerns.

Systematic Review Tier 1

A systematic review of the potential neurotoxicity of micro-and nanoplastics: the known and unknown

This critical review of 234 studies found that micro- and nanoplastics can reach the brain via olfactory translocation or by crossing the blood-brain barrier, where they may cause neuroinflammation, oxidative damage, and behavioral changes in animal models. The evidence raises significant concerns about potential neurotoxic effects of chronic microplastic exposure in humans, though major knowledge gaps remain.

Systematic Review Tier 1

The neurotoxic threat of micro- and nanoplastics: evidence from In Vitro and In Vivo models

This systematic review examined 26 studies showing that micro- and nanoplastics can cross into the brain, damage neurons, and trigger inflammation in lab and animal models. These findings raise concerns that long-term plastic exposure could contribute to neurological problems in humans, though more research is needed.

Systematic Review Tier 1

A systematic review of the potential neurotoxicity of micro-and nanoplastics: the known and unknown

This systematic review summarizes 234 research studies on how micro- and nanoplastics may harm the brain and nervous system. Evidence from animal and lab studies suggests these particles can reach the brain, potentially through the nose or by crossing the blood-brain barrier, and may cause inflammation and damage to nerve cells.

Systematic Review Tier 1

A systematic review of the potential neurotoxicity of micro-and nanoplastics: the known and unknown

This systematic review summarizes 234 research studies on how micro- and nanoplastics may harm the brain and nervous system. Evidence from animal and lab studies suggests these particles can reach the brain through the nose or by crossing the blood-brain barrier, potentially causing inflammation, oxidative stress, and nerve cell damage.

Share this paper