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Advancing pyrolysis-gas chromatography-mass spectrometry for the accurate quantification of micro- and nanoplastics in human blood

Microplastics and Nanoplastics 2025 1 citation ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Federica Nardella, Martin Brits, Martin J. M. van Velzen, Martin J. M. van Velzen, Lorenzo Scibetta, Lorenzo Scibetta, Amanda Durkin, Amanda Durkin, Roel Vermeulen, Frederic Béen, Sicco H. Brandsma, M.H. Lamoree

Summary

Researchers developed and refined pyrolysis-gas chromatography-mass spectrometry (a technique that heats plastics to identify their chemical fingerprints) to more accurately measure micro- and nanoplastics directly in human blood. Improving this method is critical because reliable detection in biological samples is a key step toward understanding how much plastic exposure humans are actually experiencing.

Models

The online version contains supplementary material available at 10.1186/s43591-025-00152-7.

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