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Effect of extreme high and low water pH on physico-chemical parameter and ALT, AST activity of Labeo rohita and its recovery
Summary
The freshwater fish Labeo rohita was exposed to 13 different pH values ranging from 4.5 to 10 to assess effects on ALT and AST enzyme activities as markers of liver function. Extreme pH values in both acidic and alkaline ranges disrupted liver enzyme activity, with partial recovery observed after a 14-day recovery period in normal water.
The chronic or sub-lethal toxicity test was performed on fish, Labeo rohita (weight 5.05±0.02g, length 7±0.03 cm) with thirteen different pH values such as 4.5, 5, 7 (Control), 9.5 and 10. Fish were fed pelleted feed with 35% crude protein. The alanine-amino-transferase (ALT) activities were lower at pH 4.5 and pH 10, and higher at pH 9.5. While Aspartate-amino-Transferase (AST) activities were lower at pH 4.5 and pH 5, and higher at pH 7 (control). The ALT activity recovered after 14 days recovery test in tap water (pH 8.2) of the fish group exposed to pH 9.5. While no AST activity recovery observed. Dissolved oxygen (DO) was highest and there was no ammonia-nitrogen (NH3-N) at pH 7 (control). While the alkalinity contents in water were highest at basic pH 9.5 and pH 10.
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