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Polymer bead size revealed via neural network analysis of single-entity electrochemical data

The Analyst 2024 2 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Gabriel Gemadzie, Baosen Zhang, Aliaksei Boika

Summary

A neural network was trained to extract microplastic particle size from electrochemical current-spike data recorded when individual polymer beads collide with a microelectrode — a method that avoids the need for optical microscopy. Accurate near-real-time sizing of microplastics in solution is an important analytical advance for water quality monitoring, where detecting and characterizing small plastic particles quickly and affordably remains a major technical challenge.

Body Systems

Single-entity electrochemistry methods for detecting polymer microbeads offer a promising approach to analyzing microplastics. However, conventional methods for determining microparticle size face challenges due to non-uniform current distribution across the surface of a sensing disk microelectrode. In this study, we demonstrate the utility of neural network (NN) analysis for extracting the size information from single-entity electrochemical data (current steps). We developed fully connected regression NN models capable of predicting microparticle radii based on experimental parameters and current-time data. Once trained, the models provide near-real-time predictions with good accuracy for microparticles of the same size, as well as the average size of two different-sized microparticles in solution. Potential future applications include analyzing various bioparticles, such as viruses and bacteria of different sizes and shapes.

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