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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Sign in to save

Biocatalysis for industry, medicine and the circular economy: general discussion

Faraday Discussions 2024 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Abdulrahman Alogaidi, Fräser A. Armstrong, Amulyasai Bakshi, Uwe T. Bornscheuer, Gareth Brown, Isabelle Bruton, Dominic J. Campopiano, Daniel F. A. R. Dourado, Friedrich Johannes Ehinger, Sabine L. Flitsch, Artur Góra, Anthony P. Green, Donald Hilvert, Sumire Honda, Meilan Huang, Rhiannon E. H. Jones, Thomas King, Bruce R. Lichtenstein, Michal Lihan, Louis Y. P. Luk, Tara C. Lurshay, Stefan Lutz, E. Neil G. Marsh, Alexander McKenzie, Ben Orton, Joelle N. Pelletier, Agata Raczyńska, Lubomı́r Rulı́šek, Peter Stockinger, Per‐Olof Syrén, Nicholas J. Turner, Francesca Valetti, Marc W. van der Kamp, Lu Shin Wong

Summary

This discussion explores the concept of using PETase enzymes to break down microplastic particles found in human blood, examining the potential and complications of such an approach. Researchers debated the feasibility of deploying biocatalytic solutions inside the human body to address plastic contamination. The conversation highlights both the promise and the significant technical hurdles involved in applying enzyme-based approaches to microplastic pollution in biological systems.

Models
Human

Michal Lihan opened a general discussion of the paper by Per-Olof Syrén: This is a very fascinating proof-of-concept study illustrating how PETases could be employed to tackle microplastic particles in human blood (https://doi.org/10.1039/d4fd00014e). This brings with it a number of complicatio

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