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Cancer may be induced by microplastics-sorbed polycyclic aromatic hydrocarbons?
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This review explores the potential link between microplastics that have absorbed polycyclic aromatic hydrocarbons and cancer risk in humans. Researchers found that microplastics can act as carriers for persistent organic pollutants, and laboratory studies suggest these contaminated particles may enhance metastatic characteristics in cancer cells. The study indicates that the combination of microplastics and adsorbed pollutants may pose a heightened concern for human health.
• MPs are plastics that originated from the breakdown of larger plastic waste. • MPs are particles of plastics with size ranging from 1 nm to 5 mm. • Persistent organic pollutants compounds leading to various cancers. • MPs boosted metastatic characteristics in cancer cells. • MPs-PAH have a high tendency to induce cancer risk in humans.
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Researchers assessed the cancer risk of microplastics originating from e-waste that had adsorbed carcinogenic polycyclic aromatic hydrocarbons (PAHs). The study found that microplastics effectively captured PAHs through adsorption and estimated the probable cancer risk from human ingestion of PAH-enriched microplastics, suggesting this exposure pathway warrants further health risk evaluation.
Microplastics-sorbed phenanthrene and its derivatives are highly bioaccessible and may induce human cancer risks
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Comment on “cancer may be induced by microplastics-sorbed polycyclic aromatic hydrocarbons?”
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This commentary examines the plausibility of microplastics acting as carriers of carcinogenic polycyclic aromatic hydrocarbons that could induce oral cancer, reviewing evidence on microplastic ingestion, tissue distribution, and the genotoxic potential of sorbed compounds. The author calls for mechanistic studies to clarify cancer risk pathways.
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A review of human and animals exposure to polycyclic aromatic hydrocarbons: Health risk and adverse effects, photo-induced toxicity and regulating effect of microplastics
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